Formulation and Pharmacokinetic Evaluation of Microcapsules Containing Pravastatin Sodium Using Rats

Table 6

Pharmacokinetic parameters.

Product			AUC	% relative BA	Elimination rate constant	Biological half-life	Vd	Ka	MRT	Cl
Test	0.072 µg/mL	4 h	0.812 µg/mL	90.38	0.14/h	4.95 h	16 L	0.57/h	6.3 h	0.293 h/mL
Std	0.07 µg/mL	2 h	0.734 µg/mL	—	0.15/h	2.9 h	12 L	0.50/h	3.5 h	0.251 h/mL