Formulation and Pharmacokinetic Evaluation of Microcapsules Containing Pravastatin Sodium Using Rats

<table class="table-group" id="tab7"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Parameter</td><td class="align_center">Initial</td><td class="align_center">After 3 months</td><td class="align_center">After 6 months</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">Drug entrapment efficiency (%)</td><td class="align_center">98.9 ± 0.1</td><td class="align_center">98.4 ± 0.2</td><td class="align_center">98.0 ± 0.1</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Stability data of most satisfactory f6 formulation.

Scientifica

tab7

Table 7

Table 7: Formulation and Pharmacokinetic Evaluation of Microcapsules Containing Pravastatin Sodium Using Rats 