Research Article

Formulation and Pharmacokinetic Evaluation of Microcapsules Containing Pravastatin Sodium Using Rats

Table 8

Dissolution data of formulation f6 after stability studies.

Time (h)InitialAfter 3 monthsAfter 6 months
30 ± 2˚C/65 ± 5% RH30 ± 2˚C/65 ± 5% RH
% CDR% CDR% CDR

124.6 ± 0.123.2 ± 0.322.0 ± 0.6
239.1 ± 0.938.7 ± 0.538.1 ± 0.1
345.0 ± 1.043.0 ± 0.142.8 ± 0.5
450.0 ± 0.149.8 ± 0.549.1 ± 0.7
551.8 ± 0.550.1 ± 0.249.0 ± 0.8
654.9 ± 0.454.0 ± 0.353.9 ± 0.7
769.3 ± 0.368.9 ± 0.768.0 ± 0.4
875.0 ± 0.274.9 ± 0.874.8 ± 0.3