Research Article

Prediction of G Protein-Coupled Receptors with SVM-Prot Features and Random Forest

Table 1

The number of proteins and composition for every class of GPCRs (from GPCRdb).

GPCRdb familyNumber of proteins (human)Composition

Class A (rhodopsin)16526 (311)Aminergic receptors, peptide receptors, protein receptors, lipid receptors, melatonin receptors, nucleotide receptors, steroid receptors, alicarboxylic receptors, sensory receptors, orphan receptors, and others
Class B1 (secretin)748 (15)Peptide receptors
Class B2 (adhesion)381 (33)Orphan receptors
Class C (glutamate)1038 (22)Ion receptors, amino acid receptors, sensory receptors, and orphan receptors
Class F (frizzled)48 (11)Peptide receptors
Other GPCRs37 (6)Orphan receptors