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Volume 2016, Article ID 9176273, 4 pages
Research Article

In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains

1Department of Pharmacology & Toxicology, College of Pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia
2Division of Pharmaceutical Biotechnology, Department of Pharmaceutics, College of Pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia

Received 1 December 2015; Revised 31 January 2016; Accepted 15 February 2016

Academic Editor: Qian Wang

Copyright © 2016 Mohammad Firoz Alam et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The objective of this investigation was to predict the antibacterial properties of sodium selenite against selected human pathogens. A group of six human bacterial pathogens including Staphylococcus aureus, Streptococcus pyogenes, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella planticola were utilized for screening. The spectrum of activity was qualified based on zone of inhibition. Our study demonstrated that sodium selenite exhibits a strong spectrum of activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Klebsiella planticola. The spectrum of activity was compared with standard ciprofloxacin disc (5 μg/disc) and observed to have satisfactory effect.