Clinical Study
Serum Level of the Angiotensin-Converting Enzyme in Patients with Idiopathic Acute Optic Neuritis: A Case-Control Study
Table 1
Demographics and clinical findings in the idiopathic acute ON group.
| | Characteristic | Total (n = 65) | Male (n = 16) | Female (n = 49) | value |
| | Age (years) | | | | | | Mean (SD) | 29.70 (8.30) | 29.37 (4.95) | 29.80 (9.18) | 0.81 | | Median (min-max) | 28 (14–49) | 29.5 (18–37) | 28 (14–49) | |
| | Affected eye, n (%) | | | | | | Right | 31 (47.7) | 6 (19.4) | 25 (51) | 0.34 | | Left | 34 (52.3) | 10 (80.6) | 24 (49) | |
| | Visual acuity, n (%) | | | | | | Mild-no impairment | 12 (18.5) | 2 (12.5) | 10 (20.4) | 0.32 | | Moderate VI | 17 (26.2) | 5 (31.3) | 12 (24.5) | | | Severe VI | 18 (27.7) | 3 (18.8) | 15 (30.6) | | | Blind-LP | 15 (23.1) | 4 (25) | 11 (22.4) | | | Blind-NLP | 3 (4.6) | 2 (12.5) | 1 (2.0) | |
| | RAPD, n (%) | | | | | | 1+ | 2 (3.1) | 1 (6.25) | 1 (2.04) | 0.78 | | 2+ | 19 (29.2) | 6 (37.5) | 13 (26.5) | | | 3+ | 29 (44.6) | 6 (37.5) | 22 (44.9) | | | 4+ | 3 (4.6) | 2 (12.5) | 2 (4.1) | | | Not reliable | 12 (18.5) | 1 (6.25) | 11 (22.46) | |
| | Disc swelling, n (%) | | | | | | Positive | 12 (18.5) | 3 (18.8) | 9 (18.4) | 0.97 | | Negative | 53 (81.5) | 13 (81.2) | 40 (84.6) | |
|
|
Independent samples t-test. Chi-square test. AON: acute optic neuritis; VI: visual impairment; LP: light perception; NLP: no light perception; RAPD: relative afferent pupil defect. |
