Serum Level of the Angiotensin-Converting Enzyme in Patients with Idiopathic Acute Optic Neuritis: A Case-Control Study

Table 2

Correlation of the clinical characteristics of idiopathic acute ON patients with serum ACE level.

Variable	Serum ACE;Median (min-max)	P value
Sex
Male	33.50 (29.1–540.0)	0.77
Female	33.50 (25.9–509.6)
Affected eye
Right	32.90 (26.90–216.70)	0.29
Left	36.20 (25.9–540.0)
Visual acuity classification
Mild-No impairment	51.30 (27.20–540)
Moderate VI	33.30 (26.90–220.80)	0.03
Severe VI	31.75 (28.30–176.30)
Blind-LP	35.70 (25.90–509.60)
Blind-NLP	29.10 (28.30–30.60)
RAPD
1+	283.45 (26.9–540.0)
2+	33.3 (27.2–188.1)	0.85
3+	32.55 (25.9–220.8)
4+	29.85 (28.7–46.1)
Not reliable	32.2 (25.9–540.0)
Disc swelling
Positive	37.50 (27.2–53.4)	0.93
Negative	33.1 (25.9–540.0)

Mann–Whitney test. Kruskal–Wallis test. ON: optic neuritis; VI: visual impairment; LP: light perception; NLP: no light perception; RAPD: relative afferent pupil defect.