Clinical Study
Serum Level of the Angiotensin-Converting Enzyme in Patients with Idiopathic Acute Optic Neuritis: A Case-Control Study
Table 2
Correlation of the clinical characteristics of idiopathic acute ON patients with serum ACE level.
| Variable | Serum ACE;Median (min-max) | P value |
| Sex | | | Male | 33.50 (29.1–540.0) | 0.77 | Female | 33.50 (25.9–509.6) | |
| Affected eye | | | Right | 32.90 (26.90–216.70) | 0.29 | Left | 36.20 (25.9–540.0) | |
| Visual acuity classification | | | Mild-No impairment | 51.30 (27.20–540) | | Moderate VI | 33.30 (26.90–220.80) | 0.03 | Severe VI | 31.75 (28.30–176.30) | | Blind-LP | 35.70 (25.90–509.60) | | Blind-NLP | 29.10 (28.30–30.60) | |
| RAPD | | | 1+ | 283.45 (26.9–540.0) | | 2+ | 33.3 (27.2–188.1) | 0.85 | 3+ | 32.55 (25.9–220.8) | | 4+ | 29.85 (28.7–46.1) | | Not reliable | 32.2 (25.9–540.0) | |
| Disc swelling | | | Positive | 37.50 (27.2–53.4) | 0.93 | Negative | 33.1 (25.9–540.0) | |
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Mann–Whitney test. Kruskal–Wallis test. ON: optic neuritis; VI: visual impairment; LP: light perception; NLP: no light perception; RAPD: relative afferent pupil defect. |