Research Article

Potential and Comparative Tablet Disintegrant Properties of Pectin Obtained from Five Okra Genotypes in Ghana

Table 4

Physical and mechanical properties of paracetamol batches produced using different concentrations of the okra pectin as disintegrant.

Formulation codeAverage weight (g) n = 20Tablet thickness (mm) n = 20Tablet diameter (mm) n = 20Hardness (kg/F) n = 6Friability (%)Disintegration time (DT) (min) n = 2Drug content (%) n = 3

F10.630 ± 0.0033.70 ± 0.09313.07 ± 0.2355.60 ± 0.5390.33011.40 ± 0.26599.61 ± 0.03
F20.630 ± 0.0013.98 ± 0.07313.04 ± 0.0094.88 ± 1.3080.13914.20 ± 0.39899.61 ± 0.07
F30.620 ± 0.0013.78 ± 0.14513.03 ± 0.0157.38 ± 2.460.00510.40 ± 0.447100.12 ± 0.01
F40.620 ± 0.0013.61 ± 0.09213.06 ± 0.0255.92 ± 1.2640.0028.90 ± 0.56699.92 ± 0.10
F50.621 ± 0.0023.96 ± 0.10413.08 ± 0.0516.44 ± 1.4050.01119.20 ± 0.10099.82 ± 0.03
F60.620 ± 0.0013.76 ± 0.09913.07 ± 0.0254.02 ± 0.8610.0059.87 ± 0.64099.75 ± 0.08
F70.630 ± 0.0023.74 ± 0.04313.03 ± 0.0116.4 ± 0.570.00010.60 ± 0.14899.82 ± 0.10
F80.632 ± 0.0023.87 ± 0.13213.02 ± 0.0854.92 ± 0.7190.0029.09 ± 0.12299.30 ± 0.04
F90.629 ± 0.0023.88 ± 0.11213.04 ± 0.0158.14 ± 2.5190.00211.08 ± 0.89897.46 ± 0.01
F100.631 ± 0.0023.95 ± 0.10913.05 ± 0.0178.60 ± 2.7420.00512.22 ± 0.86798.26 ± 0.03
F110.631 ± 0.0053.94 ± 0.13413.04 ± 0.0176.74 ± 2.7030.00919.39 ± 0.14599.59 ± 0.11
F120.621 ± 0.0023.78 ± 0.08713.05 ± 0.4014.62 ± 0.5630.1749.39 ± 1.0799.56 ± 0.03
F130.629 ± 0.0013.68 ± 0.09413.05 ± 0.0126.56 ± 0.4670.26510.98 ± 0.98999.71 ± 0.01
F140.621 ± 0.0023.87 ± 0.06813.09 ± 0.0256.20 ± 0.6630.7428.78 ± 1.02399.00 ± 0.10
F150.630 ± 0.0033.67 ± 0.09613.07 ± 0.0187.34 ± 2.0620.01710.53 ± 0.89597.63 ± 0.20
F160.630 ± 0.0023.72 ± 0.20313.04 ± 0.0083.74 ± 1.1520.00210.49 ± 1.02399.29 ± 0.03
F170.631 ± 0.0033.88 ± 0.13813.08 ± 0.0137.10 ± 0.8660.25625.04 ± 0.987101.36 ± 0.02
F180.639 ± 0.0023.82 ± 0.06713.08 ± 0.0457.42 ± 0.2870.1969.05 ± 0.98999.00 ± 0.11