Synthesis and Diuretic Activity of Substituted 1,3,4-Thiadiazoles

Table 3

Calculated urinary excretion, diuretic action, and activity of the test compounds.

Group	Urinary excretion (%)	Diuretic action	Diuretic activity
Cont.	116.7	1
Fr10	316.7	2.71	1
CPD-І	238.8	2.05	0.75
CPD-II	253.3	2.17	0.80
CPD-III	187.3	1.60	0.59
CPD-IV	260.6	2.23	0.82
CPD-V	232.7	1.99	0.73
CPD-VI	182.1	1.56	0.56
CPD-VII	192.3	1.65	0.61