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Age (years) | Exercise/physical activity | Inflammatory markers | References |
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74.3 ± 2.7 | Moderate or strenuous activity (hand-grip strength, chair stands, and gait speed) | ↓ CRP, ↓ IL-6 | D.R. Taaffe et al. 2000 [80] |
70–79 years old | Recreational activity, house/yard work activity, work activity, and total physical activity | ↓ CRP, ↓ IL-6 | D. B. Reuben et al. 2003 [81] |
40–75 years old | Metabolic equivalent-hours (MET-hours) method | ↓ sTNF-R1, ↓ sTNF-R2, ↓ IL-6, ↓ CRP | T. Pischon et al. 2003 [82] |
70–79 years old | Physical activity questionnaire (MET-hours/weeks) physical activity from the following categories (housework, stair climbing, walking for exercise, other types of walking, aerobics/calisthenics, weight training, high-intensity exercises, moderate-intensity exercises, or work/volunteer/caregiving activities) | ↓ CRP, ↓ IL-6, ↓ TNF-α | L. H. Colbert et al. 2004 [83] |
48 ± 12 | Physical activity (MET-hour/weeks) | ↓ CRP, ↓ WBC count, ↓ TNF-α, ↓ IL-6 | C. Pitsavos et al. 2004 [84] |
63 ± 10 | Maximal exercise testing on a motor-driven treadmill or an electrically braked supine bicycle | ↓ CRP | K. Rahimi et al. 2005 [85] |
70.3 ± 4.1 69.8 ± 5.5 | Aerobic exercise treatment (cardio) or a flexibility/strength exercise treatment (flex) 3 days/week, 45 min/day for 10 months | ↓ IL-18, ↓ IL-6, ↓ CRP | M. L. Kohut et al. 2006 [62] |
18–65 years old | Physical activity test performed on a modified Monark cycle ergometer with 6 min workloads, each separated by a 1 min rest | ↓ CRP, ↓ TNF-α, ↔ IL-6, ↔ adiponectin | B. J. Arsenault et al. 2009 [86] |
76.4 ± 4.1 77.0 ± 4.4 | Walking for 150 min per week at RPE 12–13 and resistance training at RPE 15-16 | ↓ IL-8, ↔ TNF-α, ↔ sTNFr I, ↔ sTNFr II, ↔ IL-6sR, ↔ IL-1sRII, ↔ IL-1ra | K. M. Beavers et al. 2010 [87] |
>50 years old | 70% of one maximum repetition (1 RM) or less was classified as moderate intensity, while activities requiring over 70% of 1 RM were classified as vigorous intensity | ↓ CRP, ↓ IL-6, ↔ TNF-α | A. V. Sardeli et al. 2018 [88] |
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