Research Article

Effect of Bronchoscopist-Directed Sedation and Other Factors on Patient Comfort during Diagnostic Flexible Bronchoscopy

Table 4

Factors affecting patient comfort in sedation and nonsedation groups during flexible bronchoscopy.

CharacteristicsSedation (N = 187)Nonsedation (N = 187)
Low discomfort VAS <25, n = 103High discomfort VAS ≥25, n = 84-valueLow discomfort VAS <25, n = 67High discomfort VAS ≥25, n = 120-value

Age (mean years ± SD)50.30 ± 14.0553.27 ± 13.980.36854.61 ± 15.0654.11 ± 13.830.637
Male: female66 : 3741 : 430.036#42 : 2573 : 470.803#
Addictions, n (%)
Smokers (including ex-smokers)17 (16.5)18 (21.4)0.303#17 (25.4)33 (27.5)0.311#
Alcoholics2 (1.9)2 (2.4)0 (0)4 (3.3)
Both (smokers and alcoholics)4 (3.9)0 (0)4 (6.0)3 (2.5)
Nil addictions80 (77.7)64 (76.2)46 (68.7)80 (66.7)
Comorbidities, n (%)70 (68)56 (66.7)0.851#38 (56.7)79 (65.8)0.217#
Socioeconomic class, n (%)
Lower class2 (1.9)0 (0)0.480#0 (0)4 (3.3)0.395#
Upper lower class20 (19.4)22 (26.2)16 (23.9)27 (22.5)
Lower middle class55 (53.4)43 (51.2)42 (62.7)73 (60.8)
Upper middle class25 (24.3)19 (22.6)9 (13.4)13 (10.8)
Upper class1 (1.0)0 (0)0 (0)3 (2.5)
Indication for flexible bronchoscopy, n (%)
Tubercular39 (37.9)36 (42.9)0.475#30 (44.8)43 (35.8)0.444#
Other infections42 (40.8)27 (32.1)22 (32.8)49 (40.8)
Malignancy22 (21.4)21 (25.0)15 (22.4)28 (23.3)
Preprocedural anxiety level before examination (VAS score) (median (Q1, Q3))15 (10,20)35 (26,45)<0.00115 (10,20)35.20 (30,45)<0.001
Lignocaine dose (mean ± SD)185.83 ± 12.41185.95 ± 13.090.946190.45 ± 19.18192.83 ± 20.830.392
Bronchoscopic interventions done, n (%)
Bronchial lavage103 (100)84 (100)67 (100)120 (100)
Biopsy/TBNA13 (12.6)11 (13.1)0.923#8 (11.9)11 (9.2)0.547#
Bronchial brushing21 (20.4)19 (22.6)0.711#20 (29.9)26 (21.7)0.213#
Duration of procedure (minutes) (mean ± SD)13.92 ± 4.85614.64 ± 6.070.15114.37 ± 4.9313.58 ± 5.220.952
Procedure-related adverse events during or in the immediate postprocedure period23 (22.3)18 (21.42)0.417#12 (17.91)17 (14.16)0.444#

#Chi-square test. Independent Student’s t-test. Mann–Whitney U test.