Relationships between Obstructive Sleep Apnea Syndrome, Continuous Positive Airway Pressure Treatment, and Inflammatory Cytokines

Table 3

Characteristics of OSAS patients before and after three months of CPAP treatment.

	Pretreatment	Posttreatment	𝑃 values
TNF-α (pg/mL)	0.131 ± 0.171	0.081 ± 0.036	0.279
IL-6 (pg/mL)	0.062 ± 0.077	0.060 ± 0.013	0.137
Minimum SaO2 (%)	71.9 ± 10.3	87.7 ± 5.7	0.137
Mean SaO2 (%)	88.2 ± 3.13	94.1 ± 1.7	0.042
SaO2 ≥ 90 (% TST)	47.7 ± 29.9	96.3 ± 6.6	<0.001
REM (%)	11.1 ± 6.8	20.4 ± 8.4	<0.001
NREM3 (%)	5.0 ± 5.2	7.4 ± 8.1	<0.001
ESS	10.9 ± 5.8	8.9 ± 5.7	<0.001
AHI (events/h)	43.7 ± 21.8	3.0 ± 3.0	<0.001
BMI (kg/m^2)	33 ± 4	32 ± 3.5	0.137
WC (cm)	114.8 ± 5.3	112.9 ± 6.1	0.182
NC (cm)	44.6 ± 2.9	44.3 ± 3.0	0.201

AWC: waist circumference; NC: neck circumference; BMI: body mass index; AHI: apnea-hypopnea index; Minimum SaO₂: the lowest oxygen saturation recorded during sleep; mean SaO₂: the average oxygen saturation recorded during sleep; SaO₂ ≥ 90 (% TST): the amount of total sleep time spent at ≥90% saturation; ESS: Epworth sleepiness scale.