Computer-Assisted Diagnosis of the Sleep Apnea-Hypopnea Syndrome: A Review

Table 8

Validation of comprehensive approaches (see text for details). = number of participants/recordings; A = Apnea; H = Hypopnea; OH = Obstructive Hypopnea; CH = Central Hypopnea; MH = Mixed Hypopnea; CA = Central Apnea; OA = Obstructive Apnea; MA = mixed apnea; AUC = areas under ROC curve; ACC = accuracy; S = single validation set.

Study source	Database	/ratio male	Age (mean ± std.)	AHI; (mean ± std.)	Reference test	Event definition	Number of events	Sensitivity (%)	Specificity (%)	Others	Validation
Fernández-Leal and Moret-Bonillo [87]	Complejo Hospitalario Universitario de A Coruña, Spain	10/—	—	—	Same-night Level 1 PSG	System SAMOA [90, 91]	1243	91.3 (OA); 100 (CA); 83.7 (MA); 91.1 (OH); 100 (CH); 60.0 (MH)	93.6 (OA); 95.7 (CA); 99.8 (MA); 98.3 (OH); 98.7 (CH); 99.9 (MH)	AUC =; 0.92 (OA); 0.98 (CA); 0.92 (MA); 0.95 (OH); 0.99 (CH) 0.80 (MH)	—
Guimaraes et al. [89]	—	3/—	—	—	Same-night PSG (unknown level)	—	—	76.2 (Events)	75.8 (Events)	—	S
Cabrero-Canosa et al. [90, 91]	Complejo Hospitalario Universitario de A Coruña, Spain	13/—	—	—	Same-night Level 1 PSG	—	1270	87.5 (Diagnosis/—)	100 (Diagnosis/—)	ACC =; 0.94 (Events); 0.80 (O); 0.92 (C); 0.85 (M); 0.92 (Diagnosis/—)	S
Alvarez-Estevez [92],; Moret-Bonillo et al. [93]	Sleep Heart Health Study [72]	26/0.69	68.5 ± 7.7	50.0 ± 30.5	Same-night Level 2 PSG	Sleep Heart Health Study, reading center manual of operations [4]	8705	81.3 (events); 89.2 (A); 89.0 (H); 83.8 (OA); 78.3 (CA); 100 (diagnosis/10)	91.6 (Events); 89.0 (A); 89.2 (H); 78.3 (OA); 83.8 (CA); 33 (diagnosis/10)	ACC =; 0.89 (events); 0.89 (A); 0.89 (H); 0.82 (OA) 0.82 (CA); 0.92 (diagnosis/10)	S