Nitric Oxide Bioavailability in Obstructive Sleep Apnea: Interplay of Asymmetric Dimethylarginine and Free Radicals

<div>Oxidative stress and high ADMA levels can cause endothelial dysfunction in OSA. ADMA: asymmetric dimethylarginine; eNOS: endothelial nitric oxide synthase; NO: nitric oxide; ONOO<sup>−</sup>: peroxynitrite; OSA: obstructive sleep apnea; ROS: reactive oxygen species.</div>

Sleep Disorders

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Figure 2: Nitric Oxide Bioavailability in Obstructive Sleep Apnea: Interplay of Asymmetric Dimethylarginine and Free Radicals 