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Sleep Disorders
Volume 2016, Article ID 8378423, 5 pages
Research Article

Poor Sleep in Multiple Sclerosis Correlates with Beck Depression Inventory Values, but Not with Polysomnographic Data

1Interdisciplinary Center of Sleep Medicine, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany
2NeuroCure Clinical Research Center, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany
3Department of Neurology, St. Joseph Hospital Berlin-Weissensee, 13088 Berlin, Germany
4CRO SOSTANA GmbH and Charité University Medicine Berlin, Wildensteiner Straße 27, 10318 Berlin, Germany
5Clinical and Experimental Multiple Sclerosis Research Center, Department of Neurology, Charité University Medicine Berlin, 10117 Berlin, Germany
6Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité University Medicine Berlin, 13125 Berlin, Germany

Received 26 September 2015; Revised 20 December 2015; Accepted 22 December 2015

Academic Editor: Luigi Ferini-Strambi

Copyright © 2016 Christian Veauthier et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. Pittsburgh Sleep Quality Index (PSQI) values correlate with depression, but studies investigating the relationship between PSQI values and polysomnographic (PSG) data showed inconsistent findings. Methods. Sixty-five consecutive patients with multiple sclerosis (MS) were retrospectively classified as “good sleepers” (GS) (PSQI ≤ 5) and “poor sleepers” (PS) (PSQI > 5). The PSG data and the values of the Visual Analog Scale (VAS) of fatigue, Modified Fatigue Impact Scale (MFIS), Fatigue Severity Scale (FSS), Epworth Sleepiness Scale (ESS), and the Beck Depression Inventory (BDI) were compared. Results. No significant differences were found either for PSG data or for ESS, MFIS, and FSS values; but PS showed significantly increased BDI and VAS values. Conclusions. Poor sleep is associated with increased depression and fatigue scale values.