Figure 3: Network analysis found four serotonin receptors, HTR1B, SLC6A4, HTR2A, and HTR2C, significantly associated with OSA. Ingenuity Pathway Analysis was used to create a network analysis. Links of validated genes (in grey) and other genes or molecules are represented with a continuous (direct interaction) or discontinuous line (indirect interaction). The expression of our candidate genes could be modulated mainly by 3 molecules: 5-hydroxytryptamine (for HTR1B and SLC6A4), PRL (HTR2A and HTR2C), and HSP90AB1 (for SL6CA4).