Selected genes associated with OSA
APOA5: apolipoprotein A-V
ADRA1B: adrenoceptor alpha 1B
ADRA2A: adrenoceptor alpha 2A
ADRB1: adrenoceptor beta 1
ADRB2: adrenoceptor beta 2, surface
ECE1: endothelin converting enzyme 1
EDNRA: endothelin receptor type A
EDN1: endothelin 1
HIF1A: hypoxia inducible factor 1, alpha subunit
HTR1B: 5-hydroxytryptamine (serotonin) receptor 1B
HTR2A: 5-hydroxytryptamine (serotonin) receptor 2A
HTR2C: 5-hydroxytryptamine (serotonin) receptor 2C
HTR3A: 5-hydroxytryptamine (serotonin) receptor 3A
HTR3B: 5-hydroxytryptamine (serotonin) receptor 3B
HTR3C: 5-hydroxytryptamine (serotonin) receptor 3C
HTR3D: 5-hydroxytryptamine (serotonin) receptor 3D
HTR3E: 5-hydroxytryptamine (serotonin) receptor 3E
IRS1: insulin receptor substrate 1
LEP: leptin
LEPR: leptin receptor
LIPC: lipase, hepatic
LPL: lipoprotein lipase
NOS3: nitric oxide synthase 3 (endothelial cell)
SLC6A4: solute carrier family 6 (neurotransmitter transporter), member 4
Box 1: Top 23 candidate genes identified by enrichment analysis. The box shows the 23 unique genes (in alphabetical order) identified from Enrichr analysis. The majority of the pathway genes are involved in serotonin based regulatory pathways.