Research Article

Daytime QT by Routine 12-Lead ECG Is Prolonged in Patients with Severe Obstructive Sleep Apnea

Table 3

Odds ratio of abnormal QTc based on comorbidity.

Initial analysisOdds ratio95% CI value
 Moderate vs. normal-mild OSA0.780.36-1.670.19
 Severe vs. normal-mild OSA1.440.72-2.920.1
 BMI (kg/m2)0.990.95-1.020.4
 Age (years)0.990.97-1.020.6
 Hypertension1.360.66-2.880.41
 HF4.072.1-8.06<0.0001
Subsequent analysis (dichotomous groups)Odds ratio95% CI value
 Severe vs. nonsevere OSA2.681.34-5.480.0058
 BMI (kg/m2)0.960.92-10.05
 Age (years)0.990.96-1.020.62
 Hypertension1.420.59-3.670.45
 HF5.412.63-11.35<0.0001

Classification of apnea-hypopnea index (AHI) in trichotomous stratification: normal-mild: <15/hr, moderate: 15-30/hr, and severe: >30/hr. For dichotomous stratification: nonsevere: <30/hr (i.e., normal-mild and moderate), severe: >30/hr. OSA = obstructive sleep apnea; BMI = body mass index; HF = heart failure; CI = confidence interval.