ACT-SVM: Prediction of Protein-Protein Interactions Based on Support Vector Basis Model

Table 3

Comparison of features.

Dataset	Classifier	Method	AUC	Acc	MCC	Sn	Sp
H. pylori	ANN	FCTP	0.6772	0.6137	0.2337	0.5009	0.7268
		ACT	0.7412	0.6738	0.3544	0.5780	0.7698
	SVM	FCTP	0.7038	0.6549	0.3099	0.6535	0.6564
		ACT	0.8010	0.7279	0.4558	0.7238	0.7320
	KNN	FCTP	0.5747	0.5554	0.1148	0.6913	0.4192
		ACT	0.7746	0.7056	0.4176	0.7942	0.6168
	RF	FCTP	0.7553	0.6601	0.3372	0.5043	0.8162
		ACT	0.7815	0.7030	0.4104	0.6312	0.7749
	LR	FCTP	0.6866	0.62578	0.2547	0.5489	0.7027
		ACT	0.6969	0.6266	0.2602	0.5129	0.7406
	NB	FCTP	0.5186	0.5013	0.0024	0.6072	0.3952
		ACT	0.6378	0.6043	0.2089	0.5780	0.6306
Human	ANN	FCTP	0.8980	0.8275	0.6541	0.8024	0.8504
		ACT	0.8819	0.8008	0.6007	0.7883	0.8122
	SVM	FCTP	0.8320	0.7582	0.5150	0.7274	0.7864
		ACT	0.8938	0.8388	0.6791	0.7774	0.8950
	KNN	FCTP	0.9373	0.8557	0.7181	0.7652	0.9384
		ACT	0.9165	0.8118	0.6444	0.6575	0.9531
	RF	FCTP	0.8950	0.8112	0.6247	0.7357	0.8803
		ACT	0.8875	0.7849	0.5812	0.6511	0.9073
	LR	FCTP	0.8180	0.7444	0.4873	0.7146	0.7717
		ACT	0.8177	0.7505	0.5001	0.6915	0.8046
	NB	FCTP	0.6472	0.6414	0.3525	0.2822	0.9701
		ACT	0.6089	0.6105	0.2642	0.2527	0.9378