Use Chou’s 5-Step Rule to Classify Protein Modification Sites with Neural Network

Table 6

The testing scores based on different proportion of positive and negative samples.

Scale-up ratio	AUC	Acc (%)	MCC	Sn (%)	Sp (%)	F1
1:1	0.7471	63.54	0.2002	74.16	62.65	67.92
1:2	0.7399	76.67	0.1982	52.99	78.65	63.32
1:3	0.7324	82.60	0.1828	38.61	86.28	53.35
1:4	0.7290	84.33	0.1689	32.65	88.64	47.72
1:5	0.7228	85.54	0.1623	28.93	90.26	43.82
1:6	0.7205	86.71	0.1476	24.13	91.94	38.23
1:7	0.7196	87.27	0.1499	23.12	92.62	37.00
1:8	0.7193	86.64	0.1539	25.18	91.77	39.52
1:9	0.7012	87.32	0.1340	20.91	92.86	34.13
1:10	0.6984	88.08	0.1382	19.61	93.80	32.44
1:11	0.6972	88.96	0.1337	16.87	94.97	28.65
1:12	0.7033	89.43	0.1292	15.10	95.64	26.08