A Crossover Comparison of the Sensitivity and the Specificity between BIS and AEP in Predicting Unconsciousness in General Anesthesia

Table 10

Propofol/sevoflurane concentration, BIS/AEP values, and prediction probabilities at sedation (mean (95% CI).

	EC5		EC50		EC95		Sensitivity (%)		Specificity (%)		Prediction probability
	Propofol	Sevoflurane	Propofol	Sevoflurane	Propofol	Sevoflurane	Propofol	Sevoflurane	Propofol	Sevoflurane	Propofol	Sevoflurane
Blood concentration (g/ml)/Fi (%)	0.9	1.2	1.7 (1.5–1.9)	2.5 (2.4–2.7)	2.6	3.9	92	82	64	72	0.78	0.75
Effect-site concentration (g/ml)/ET (%)	0.6	0.6	1.1 (1.1–1.2)	1.6 (1.5–1.7)	1.6	2.5	73	76	77	75	0.77	0.76
BIS	90	100	81 (80–82)	85 (82–87)	71	60	80	63	77	84	0.78	0.73
AEP	100	96	56 (52–60)	62 (58–65)	11	27	76	82	75	69	0.76	0.76