A Crossover Comparison of the Sensitivity and the Specificity between BIS and AEP in Predicting Unconsciousness in General Anesthesia

Table 12

Propofol/sevoflurane concentration, BIS/AEP values, and prediction probabilities at anesthesia (mean (95% CI).

	EC5		EC50		EC95		Sensitivity (%)		Specificity (%)		Prediction probability
	Propofol	Sevoflurane	Propofol	Sevoflurane	Propofol	Sevoflurane	Propofol	Sevoflurane	Propofol	Sevoflurane	Propofol	Sevoflurane
Blood concentration (g/ml)/Fi (%)	2.3	2.4	4 (3.7–4.2)	3.9 (3.8–4.1)	5.6	5.4	89	79	73	73	0.81	0.76
Effect-site concentration (g/ml)/ET (%)	1.7	1.6	3.1 (3–3.1)	3 (2.8–3.1)	4.5	4.4	76	78	76	75	0.76	0.76
BIS	61	67	46 (45–48)	39 (37–42)	31	11	73	76	76	75	0.74	0.76
AEP	28	75	17 (16–18)	34 (30–37)	6	0	81	66	72	83	0.77	0.75