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Patient/gender/age at operation | Altman’s type | Initial operation | AFP level (ng/mL) Histology | Initial staging | Adjuvant therapy | Second operation | Outcomes |
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Mature teratoma (MT) and recurrence with endodermal sinus tumor (EST) |
|
1 F 3.5 y (at the recurrence) | IV | Tumor biopsy | 2,000 EST | IV (lung metastasis) | Chemotherapy + radiotherapy | None | 6-year FU Survival-NED |
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Malignant teratoma |
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1 F 2.1 y | II | Total resection + coccygectomy | 20,000 MT + EST | I | Chemotherapy | None | 3-year FU Survival-NED |
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2 F 1.2 y | IV | Tumor biopsy | 2,000 MT + EST | III | Chemotherapy + radiotherapy | Total resection + coccygectomy | 8-year FU Survival-NED |
|
3 M 9 m | IV | Partial resection + coccygectomy | 43,430 MT + EST | III | Chemotherapy + radiotherapy | Total resection | 8-year FU Survival- NED |
|
4 F 1.5 m | II | Partial resection + coccygectomy | 6,985 MT + EST | III | Chemotherapy + radiotherapy | None | 10-year FU Survival-NED |
|
5 F 1.2 y | IV | Tumor biopsy | 60,500 MT + EST | III | Chemotherapy + radiotherapy | Total resection + coccygectomy | 7-year FU Survival-NED |
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6 M 3 y | III | Tumor biopsy | 60,000 IMT grade 3 + EST | IV (lung metastasis) | Chemotherapy + radiotherapy | None | Lung metastasis Death at home after one year treatment |
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Endodermal sinus tumor |
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1 F 1.5 y | III | Partial resection + coccygectomy | 20,000 EST | III | Chemotherapy + radiotherapy | None | Lung metastasis Death at home after 2-year treatment |
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2 F 1.1 y | III | Tumor biopsy | 58,704 EST | III | Chemotherapy | Total resection + coccygectomy | Lung and brain metastases Death at home after 2-year treatment |
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3 F 2.3 y | IV | Tumor biopsy | 34,144 EST | IV (lung metastasis) | Chemotherapy + radiotherapy | Total resection + coccygectomy | 2-year FU Survival-NED |
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4 M 1.3 y | IV | Tumor biopsy | 2,207 EST | III | Chemotherapy + radiotherapy | Total resection + coccygectomy | 3-year FU Survival-NED |
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5 F 1.8 y | IV | Tumor biopsy | 51,250 EST | IV (lung metastasis) | Chemotherapy + radiotherapy | Laparotomy, colostomy, and cystostomy | Lung, long bone,and vertebral metastases Death at home after 10-month treatment |
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6 F 3.2 y | IV | Tumor biopsy | 30,763 EST | IV (vertebral metastasis) | Chemotherapy + radiotherapy | Laparotomy, partial resection, and coccygectomy | 3-year FU Survival-NED |
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