Clinical Study

Efficacy and Outcomes of Intrathecal Analgesia as Part of an Enhanced Recovery Pathway in Colon and Rectal Surgical Patients

Table 2

Comparison of various intrathecal regimens.

IA-O ()IA-L () value

Surgical approach, (%)0.15
 Open329 (60)27 (50)
 MIS218 (40)27 (50)
Incidence of ileus, (%)86 (16)9 (17)0.86
Length of stay (days), median (IQR)3 (2–5)3.5 (3–5)0.29
Pain score, median (IQR)
 4 hours3 (1–5)3 (2–5)0.52
 8 hours2 (1–4)2.5 (2–4)0.16
 16 hours3 (1–5)4 (2–7)0.10
 24 hours3 (2–5)4 (2–6)0.32
 48 hours3 (2–5)4 (2–5)0.12
 48-hour maximum6 (4–7)7 (5–8)0.045
Total OME received, median (IQR)22.5 (0–82.5)33.8 (15–98)0.06
Number of patients receiving no OME, (%)162 (30)8 (15)0.03

IA: intrathecal opioid; IA-L: intrathecal opioid + local anesthetic; MIS: minimally invasive surgery; IQR: interquartile range.