A Comparison of Treatments and Outcomes for Medullary versus Nonmedullary Colon Cancer: A Single Institutional Experience Showing a Worse Prognosis for Stage 3 Disease

Table 1

Patient characteristics for MCC vs. NMC and PD/UD NMC.

	MCC	NMC		MCC vs. NMC	MCC vs. PD/UD NMC
	Total (n = 33)	Total (n = 1775)	PD/UD (n = 292)	valuea	valueb
Age	79.3 ± 10.2	68.3 ± 13.3	70.2 ± 13.2	<0.0001	0.0002
Sex				0.001	0.020
Female	26 (78.8%)	869 (49%)	169 (57.9%)
Male	7 (21.2%)	906 (51%)	123 (42.1%)
Charlson/Deyo score				0.013	0.032
0	19 (57.6%)	1,342 (75.6%)	212 (72.6%)
1	9 (27.3%)	309 (17.4%)	62 (21.2%)
≥2	5 (15.2%)	124 (7%)	18 (6.2%)
Location primary site				0.001	0.054
Ascending colon/cecum	24 (72.7%)	744 (41.9%)	160 (54.8%)
Not ascending colon/cecum	9 (27.3%)	984 (55.4%)	130 (44.5%)
Unknown/others	0	47 (2.7%)	2 (0.7%)
Path stage				0.004	0.032
1	2 (6.1%)	287 (16.2%)	12 (4.1%)
2	12 (36.4%)	386 (21.8%)	57 (19.5%)
3	16 (48.8%)	391 (22%)	107 (36.6%)
4	1 (3%)	258 (14.5%)	62 (21.2%)
Unknown/others	2 (6.1%)	453 (25.5%)	54 (18.5%)
Grade				<0.0001	0.001
Well differentiated	0	121 (6.8%)	0
Moderately differ	0	1,113 (62.7%)	0
Poorly differentiated	12 (36.4%)	198 (11.2%)	198 (67.8%)
Undiffer/anaplastic	20 (60.6%)	94 (5.3%)	94 (32.2%)
Unknown/others	1 (3%)	249 (14%)	0

MCC, medullary colon cancer; NMC, nonmedullary colon cancer; PD, poorly differentiated; UD, undifferentiated.