A Systematic Review of Early versus Late Closure of Loop Ileostomy

Table 1

Comparison between patient baseline demographics.

Reference

Number of patients

Gender (F : M)

Age (years)

ASA

Main diagnosis

Index operation

Adjuvant radio-chemotherapy

I

II

III

IV

EC

LC

EC

LC

EC

LC

EC

LC

EC

LC

EC

LC

EC

LC

EC

LC

EC

LC

EC

LC

Danielsen et al.

55

57

56 : 44

37 : 63

67

67

22%

33%

38%

23%

33%

35%

5%

2%

Rectal cancer

TME

29%

28%

Figueiredo et al.

65^a

155^b

79

45 : 55^a

50 : 50^b

34 : 66

60^a

62^b

62

28%^a

29%^b

20%

63%^a

63%^b

67%

9%^a

8%^b

13%

—^a

—^b

—

Rectal cancer

TME

75%^a

58%^b

59%

Wanglin et al.

179

179

88 : 91

88 : 91

45.7

45.6

56.4%^c

56.4%^c

56.4%^c

56.4%^c

44%^d

44%^d

44%^d

44%^d

Cancer (20.1%) IBD (69.8%) others (10.1%)

AC/LI (36.3%) CP/IPAA (31.3%) LAR/DLI (10.1%) TP/IPAA (6.7%) others (15.6%)

AC/LI (27.9%) CP/IPAA (30.7%) LAR/DLI (11.7%) TP/IPAA (6.7%) others (22.9%)

17%

17%

Park et al.

55

57

31 : 24

21 : 36

67

67

n/r

n/r

n/r

n/r

n/r

n/r

n/r

n/r

Rectal cancer

TME

69%

68%

^aClosure before 60 days of stoma creation. ^bClosure 61–90 days after stoma creation. ^cPercentage of ASA I and II grouped together. ^dPercentage of ASA III and IV grouped together. n/r: not reported; EC: early closure; LC: late closure; TME: total mesorectal excision; CP/IPAA: complete proctectomy with ileal-pouch anal anastomosis; LAR/DLI: low anterior resection/diverting loop ileostomy; TP/IPAA: total proctocolectomy with ileal-pouch anal anastomosis; IBD: inflammatory bowel disease.