Preoperative Predictors for 90-Day Mortality after Pancreaticoduodenectomy in Patients with Adenocarcinoma of the Ampulla of Vater: A Single-Centre Retrospective Cohort Study
Table 3
Univariate and multivariable analysis for prediction of 90-day mortality after pancreaticoduodenectomy for ampullary adenocarcinoma.
Mortality
Univariate
Multivariable
No (n = 91)
Yes (n = 10)
value
value
OR
CI 95
Age (years), mean (SD)
58.7 (11.3)
68.8 (6)
0.005φ
0.077
1.1
0.99
1.2
Male sex, count (%)
41 (45.1)
6 (6)
0.508χ
Body mass index (kg/m2), mean (SD)
24.9 (4.4)
25.3 (3.1)
0.737φ
MELD score, mean (SD)
10.5 (3.9)
12.7 (5.9)
0.225φ
ALBI grade, count (%)
0.010χ
ALBI 1
29 (31.9)
1 (10)
0.037
ALBI 2
43 (47.3)
3 (30)
0.383
3.05
0.25
37.5
ALBI 3
16 (17.6)
6 (60)
0.01
21.7
2.1
226.9
Undetermined
3 (3.2)
0
ASA score, count (%)
0.024χ
0.385
ASA I
2 (2.2)
0
ASA II
70 (76.9)
4 (40)
ASA III
19 (20.9)
6 (60)
eGFR <90 mL/min/1.73 m2, count (%)
13 (14.3)
5 (50)
0.015χ
0.013
17.7
1.8
172.6
Preoperative RBC transfusion, count (%)
23 (25.3)
6 (60)
0.031χ
0.322
Preoperative biliary drainage, count (%)
27 (29.7)
0
0.720χ
Haemoglobin in g/L, mean (SD)†
116.2 (14.2)
119.6 (19.1)
0.878φ
Platelet count in 109/L, mean (SD)†
336.4 (156)
282 (89.3)
0.403φ
International Normalized Ratio, mean (SD)†
1.09 (0.1)
1.21 (0.3)
0.202φ
Prothrombin time, mean (SD)†
13 (1.7)
14.4 (2.8)
0.114φ
Serum total bilirubin in µmol/L, mean (SD)†
61.8 (79.7)
98 (107.7)
0.437φ
Serum creatinine in µmol/L, mean (SD)†
57 (14.7)
70.4 (20.9)
0.028χ
0.223
Serum glucose in µmol/L, mean (SD)†
5.5 (1.8)
4.97 (0.4)
0.322φ
Serum albumin in g/L, mean (SD)†
36.6 (5.8)
30.6 (10.4)
0.038φ
0.291
φχMann–Whitney U-test; χchi-square or Fisher’s exact test; †preoperative laboratory values. Variables with a (italics) in the univariate analysis were used for multivariable analysis. Significance was set at (marked in bold).
