Clinical Analysis on Alteration of Thyroid Hormones in the Serum of Patients with Acute Ischemic Stroke
Table 1
Characteristics of acute ischemic stroke patients with low T3 and normal T3 values.
Low T3 group
Normal T3 group
-value
( ng/dL)
( ng/dL)
Clinical variables
Age (years)
68.1 (12.7)
66.8 (11.5)
NS
Sex (% male)
18 (62.1%)
11 (61.1%)
NS
Smoking
9 (31.0%)
6 (33.3%)
NS
Hypercholesterolemia
8 (27.6%)
5 (27.8%)
NS
Coronary artery disease
5 (17.2%)
3 (16.7%)
NS
Diabetes mellitus
9 (31.0%)
6 (33.3%)
NS
Atrial fibrillation
6 (20.1%)
4 (22.2%)
NS
History of hypertension
19 (65.5%)
11 (61.1%)
NS
BP on admission
Systolic BP (mmHg)
156.2 (27.9)
150.2 (29.5)
NS
Diastolic BP (mmHg)
89.7 (11.4)
87.8 (14.2)
NS
Baseline NIHSS scores
11.5 (3.5)
6.6 (4.3)
<.05
Distribution of NIHSS scores
Mild (<8)
2 (6.9%)
15 (83.3%)
<.01
Moderate (8–14)
17 (58.6%)
2 (11.1%)
<.01
Severe (≥14)
10 (34.5%)
1 (5.6%)
<.01
Laboratory variables
Anterior carotid artery territory
11 (37.9%)
7 (38.9%)
NS
Posterior/basilar artery territory
6 (20.1%)
4 (22.2%)
NS
Thyroid function tests
TSH (U/mL)
1.24 (1.19)
1.30 (1.21)
NS
T3 (ng/dL)
53.1 (11.7)
109.5 (21.6)
<.01
T4 (ng/dL)
8.5 (3.04)
9.2 (2.6)
NS
Initial WBC count
7.8 (3.9)
7.3 (2.5)
NS
Initial hemoglobin
9.4 (1.4)
9.1 (1.8)
NS
Glucose on admission (mmol/L)
135.6 (56.8)
128.9 (55.4)
<.05
Medications
Antiplatelets/Anticoagulants
14 (48.3%)
9 (50%)
NS
Numbers for nominal data indicate percentages in parentheses and for continuous data indicate mean standard deviation. Statistical significance (). NS: no statistical significance; BP: blood pressure; NIHSS: National Institutes of Health Stroke Scale; Baseline NIHSS scores: the initial scores on admission; TSH: thyroid-stimulating hormone; T3: triiodothyronine; T4: thyroxine; Antiplatelets/Anticoagulants: ASA or Plavix or coumadin.