Stroke Research and Treatment / 2010 / Article / Tab 1

Clinical Study

Clinical Analysis on Alteration of Thyroid Hormones in the Serum of Patients with Acute Ischemic Stroke

Table 1

Characteristics of acute ischemic stroke patients with low T3 and normal T3 values.

Low T3 groupNormal T3 groupP-value
(T375 ng/dL)(T3>75 ng/dL)

Clinical variables
Age (years)68.1 (±12.7)66.8 (±11.5)NS
Sex (% male)18 (62.1%)11 (61.1%)NS
Smoking9 (31.0%)6 (33.3%)NS
Hypercholesterolemia8 (27.6%)5 (27.8%)NS
Coronary artery disease5 (17.2%)3 (16.7%)NS
Diabetes mellitus9 (31.0%)6 (33.3%)NS
Atrial fibrillation6 (20.1%)4 (22.2%)NS
History of hypertension19 (65.5%)11 (61.1%)NS
BP on admission
 Systolic BP (mmHg)156.2 (±27.9)150.2 (±29.5)NS
 Diastolic BP (mmHg)89.7 (±11.4)87.8 (±14.2)NS
Baseline NIHSS scores11.5 (±3.5)6.6 (±4.3)<.05
Distribution of NIHSS scores
 Mild (<8)2 (6.9%)15 (83.3%)<.01
 Moderate (8–14)17 (58.6%)2 (11.1%)<.01
 Severe (≥14)10 (34.5%)1 (5.6%)<.01

Laboratory variables
Anterior carotid artery territory11 (37.9%)7 (38.9%)NS
Posterior/basilar artery territory6 (20.1%)4 (22.2%)NS
Thyroid function tests
 TSH (μU/mL)1.24 (±1.19)1.30 (±1.21)NS
 T3 (ng/dL)53.1 (±11.7)109.5 (±21.6)<.01
 T4 (ng/dL)8.5 (±3.04)9.2 (±2.6)NS
Initial WBC count7.8 (±3.9)7.3 (±2.5)NS
Initial hemoglobin9.4 (±1.4)9.1 (±1.8)NS
Glucose on admission (mmol/L)135.6 (±56.8)128.9 (±55.4)<.05

Antiplatelets/Anticoagulants14 (48.3%)9 (50%)NS

Numbers for nominal data indicate percentages in parentheses and for continuous data indicate mean ± standard deviation. Statistical significance (P<.05). NS: no statistical significance; BP: blood pressure; NIHSS: National Institutes of Health Stroke Scale; Baseline NIHSS scores: the initial scores on admission; TSH: thyroid-stimulating hormone; T3: triiodothyronine; T4: thyroxine; Antiplatelets/Anticoagulants: ASA or Plavix or coumadin.

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