Research Article
A Parallel Thrombolysis Protocol with Nurse Practitioners As Coordinators Minimized Door-to-Needle Time for Acute Ischemic Stroke
Table 2
Patients treated with thrombolytic therapy.
| | 2007/10–2009/9 () | 2009/10–2010/9 () | P value |
| | Age, mean ± SD: y | | | 0.095 | | Female, n (%) | 12 (30.0) | 9 (42.9) | 0.315 | | Pretreatment NIHSS, median | 16 | 18 | 0.451 | | Time from onset to, median (IQR): min | | | | | Arrival | 38.5 (22–73) | 54 (27–103) | 0.151 | | Thrombolysis | 112.5 (95–137) | 121 (88–158) | 0.796 | | Arrival between 2 and 3 hours, n (%) | 0 (0) | 4 (19.0) | 0.012 | | Time from arrival to, median (IQR): min | | | | | CT scan | 16.5 (12–23) | 14 (11–19) | 0.248 | | PT/PTT | 52 (46–58) | 48 (39–60) | 0.288 | | Neurology evaluation | 46 (32–63) | 37 (28–43) | 0.026 | | Thrombolysis | 68.5 (57–83) | 58 (54–69) | 0.035 | | ICU admission | 133.5 (95–152) | 116 (94–143) | 0.230 | | mRS 0-1, n (%) | 14 (35.0) | 6 (28.6) | 0.611 | | SICH, n (%) | 5 (12.5) | 2 (9.5) | 1.000a |
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aFisher’s exact test.
CT: computed tomography; ICU: intensive care unit; IQR: interquartile range; mRS: modified Rankin Scale; NIHSS: National Institutes of Health Stroke Scale; PT: prothrombin time; PTT: partial thromboplastin time; SD: standard deviation; SICH: symptomatic intracerebral hemorrhage; rtPA: recombinant tissue plasminogen activator.
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