Persistent Penumbra in a Rabbit Stroke Model: Incidence and Histologic Characteristics
Figure 2
Pimonidazole stain identifies penumbra. (a) Intense staining is present in penumbra (arrow) adjacent to infarct (stars), 0.5× magnification. (b) Closeup of area within the box demonstrates intense staining adjacent to infarct, 4× magnification. (c) Diffuse weak staining (arrows) indicates mild hypoxia associated with euthanasia. Infarct does not stain (star.), 0.5× magnification. Negative control (d).
