Research Article

Functional Inflammatory Genotypes in Ischemic Stroke: Could We Use Them to Predict Age of Onset and Long-Term Outcome?

Table 2

Baseline characteristics and genotype frequencies of IS patients.

CharacteristicIS patients
( 𝑛 = 1 4 5 )

Age, median (IQR)68 (58–76)
Sex, females (%)50 (34.5)
Arterial hypertension (%)104 (72)
Diabetes mellitus (%)40 (28)
Hypercholesterolemia (%)102 (70)
Atrial fibrillation (%)31 (21)
Ischemic heart disease (%)37 (26)
Current smoking (%)52 (36)
Stroke severity on admission (%)
 Mild (SSS = 45–58)69 (48)
 Moderate (SSS = 19–44)44 (30)
 Severe (SSS = 0–18)32 (22)
TNF-α-308G>A
 GG (%)115 (79)
 GA (%)30 (21)
IL6-174G>C
 GG (%)85 (59)
 GC (%)50 (34)
 CC (%)10 (7)
IL12B 1188A>C
 AA (%)77 (53)
 AC (%)57 (39)
 CC (%)11 (8)
IL4-589C>T
 CC (%)123 (84.8)
 CT (%)22 (15.2)
IL10-1082G>A
 AA (%)47 (32.4)
 GA (%)71 (49)
 GG (%)27 (18.6)

IQR: interquartile range, IS: ischemic stroke,
SSS: scandinavian stroke scale.