Stroke Research and Treatment / 2012 / Article / Tab 1

Review Article

Asymptomatic and Symptomatic Carotid Stenosis: An Obsolete Classification?

Table 1

Outline of the most important characteristics and results of large carotid surgery trials. DSA: digital substraction angiography.

NASCETECSTACASACST

(total)2885302416623120
Observation period prior to inclusion (max.)120 days180 days120 days180 days
Ratio TIA/stroke as qualifying event prior to inclusion61%/39%50%/50%
Diagnostic method for determination of stenosis grade (SG)DSA (distal SG)DSA (local SG)Doppler sonography/DSADuplex sonography
Significant correlation of stroke risk with SGYesYesNoNo
Controlled medical treatmentNoNoNoNo
Indication for carotid surgeryLimited at 50–69% SG>70–99% SGLimited at 50–69% SG>70–99% SGNoLimited at >60–99%
Stroke risk (surgical treatment) (%)15.7 (5 yrs)8.9 (3 yrs)15.0 (5 yrs)10.5 (5 yrs)5.1 (5 yrs)6.4 (5 yrs)
Stroke risk (medical treatment) (%)22.2 (5 yrs)28.3 (3 yrs)12.1 (5 yrs)19.0 (5 yrs)11.0 (5 yrs)11.7 (5 yrs)
Absolute risk reduction (%)6.519.4−2.98.55.95.4
Relative risk reduction (%)2969455346
Numbers needed to treat155121719

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