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Stroke Research and Treatment
Volume 2012, Article ID 392101, 7 pages
Research Article

A Long-Term Follow-Up Programme for Maintenance of Motor Function after Stroke: Protocol of the life after Stroke—The LAST Study

1Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway
2Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway
3Physiotherapy Programme, Faculty of Health Science, Oslo and Akershus University College of Applied Sciences, 0130 Oslo, Norway
4Department of Geriatric Medicine, Baerum Hospital, Vestre Viken Trust, 1309 Rud, Norway
5Department of Geriatrics, University Hospital in Northern Norway, 9038 Tromsø, Norway
6Stroke Unit, Department of Medicine, St. Olavs Hospital, Trondheim University Hospital, 7006 Trondheim, Norway

Received 12 July 2012; Accepted 23 October 2012

Academic Editor: Susanne Palmcrantz

Copyright © 2012 Torunn Askim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. There are no evidence-based strategies that have been shown to be superior in maintaining motor function for months to years after the stroke. The LAST study therefore intends to assess the effect of a long-term follow-up program for stroke patients compared to standard care on function, disability and health. Design. This is a prospective, multi-site randomised controlled trial, with blinded assessment 18 months after inclusion. A total of 390 patients will be recruited and randomised to a control group, receiving usual care, or to an intervention group 10 to 16 weeks after onset of stroke. Patients will be stratified according to stroke severity, age above 80, and recruitment site. The intervention group will receive monthly coaching on physical activity by a physiotherapist for 18 consecutive months after inclusion. Outcomes. The primary outcome is motor function (Motor Assessment Scale) 18 months after inclusion. Secondary outcomes are: dependency, balance, endurance, health-related quality of life, fatigue, anxiety and depression, cognitive function, burden on caregivers, and health costs. Adverse events and compliance to the intervention will be registered consecutively during follow-up.