Fibrinolytic Activity and Platelet Function in Subjects with Obstructive Sleep Apnoea and a Patent Foramen Ovale: Is There an Option for Prevention of Ischaemic Stroke?
Table 1
Baseline characteristics of 53 subjects investigated for OSA and PFO.
Variable
OSA with PFO
OSA without PFO
Control with PFO
Control without PFO
Total
Sex (female/male)
0/3
1/20
1/5
3/20
5/48
Mean (SD) age, years
51 (3)
46 (8)
51 (15)
42 (7)
45 (9)
Mean (SD) BP, mmHg
121 (2)
115 (11)
106 (11)
112 (12)
113 (12)
Mean (SD) BMI kg/m2
31 (6)
32 (6)
27 (4)
28 (5)
30 (6)
Median (25 and 75%) AHI
19 (5, 30)
11 (8, 16)
1 (0, 2)
1 (0, 3)
4 (1, 11)
Previous history
Ischaemic vascular disease
1*
1†
0
1‡
3
Atrial fibrillation
0
0
0
1
1
Diabetes mellitus
1
3
0
0
4
Hypertension
1
9
1
3
14
Current smoking
0
5
0
3
8
BP: blood pressure, BMI: body mass index (normal weight 18.5–24.9; overweight 25–29.9; obesity > 30), RDI: respiratory disturbance index.
*Myocardial infarction. †Myocardial infarction and ischaemic brain infarction. ‡Ischaemic brain infarction.