Research Article

Fibrinolytic Activity and Platelet Function in Subjects with Obstructive Sleep Apnoea and a Patent Foramen Ovale: Is There an Option for Prevention of Ischaemic Stroke?

Table 1

Baseline characteristics of 53 subjects investigated for OSA and PFO.

VariableOSA with PFO 
OSA without PFO 
Control with PFO 
Control without PFO 
Total 

Sex (female/male)0/31/201/53/205/48
Mean (SD) age, years51 (3)46 (8)51 (15)42 (7)45 (9)
Mean (SD) BP, mmHg121 (2)115 (11)106 (11)112 (12)113 (12)
Mean (SD) BMI kg/m231 (6)32 (6)27 (4)28 (5)30 (6)
Median (25 and 75%) AHI19 (5, 30)11 (8, 16)1 (0, 2)1 (0, 3)4 (1, 11)
Previous history
 Ischaemic vascular disease1*1013
 Atrial fibrillation00011
 Diabetes mellitus13004
 Hypertension191314
 Current smoking 05038

BP: blood pressure, BMI: body mass index (normal weight 18.5–24.9; overweight 25–29.9; obesity > 30), RDI: respiratory disturbance index.
*Myocardial infarction.
Myocardial infarction and ischaemic brain infarction.
Ischaemic brain infarction.