Reducing Haemorrhagic Transformation after Thrombolysis for Stroke: A Strategy Utilising Minocycline

Table 1

Sample size calculations table according to different treatment effects.

n for a given prevalence and reduction	Power = 75%		Power = 80%		Power = 85%		Power = 90%
	25%	50%	25%	50%	25%	50%	25%	50%
0.04	3385	583	3891	670	4524	779	5389	928
0.06	2305	397	2649	456	3080	531	3669	632
0.08	1766	304	2030	350	2361	407	2812	484
0.10	1444	249	1660	286	1930	333	2299	396
0.20	812	140	934	161	1086	187	1293	223
0.30	619	107	711	123	827	143	985	170
0.40	542	93	623	107	724	125	862	149