Modification of the Ladder Rung Walking Task—New Options for Analysis of Skilled Movements
Table 1
Effect of cerebral ischemia on ladder rung walking in rats.
Foot fault score
Error rate (% of steps)
B
PI 7
PI 28
B
PI 7
PI 28
Mean ± SEM
Median
Mean ± SEM
Median
Mean ± SEM
Median
Mean ± SEM
Median
Mean ± SEM
Median
Mean ± SEM
Median
Horizontal
LFL
5.44 ± 0.14
5.47
5.28 ± 0.16
5.30
5.30 ± 0.15
5.27
3.28 ± 2.79
3.72
3.42 ± 2.59
2.57
4.73 ± 2.72
3.89
RFL
5.52 ± 0.13
5.49
4.46 ± 0.35
4.58
4.73 ± 0.34
4.90
2.10 ± 1.68
2.53
25.13 ± 9.31
23.81
14.83 ± 8.57
10.26
RHL
5.64 ± 0.11
5.63
5.11 ± 0.25
5.10
5.50 ± 0.16
5.54
3.25 ± 1.56
3.03
12.01 ± 3.87
11.60
3.80 ± 1.80
3.13
LHL
5.60 ± 0.11
5.57
5.68 ± 0.14
5.74
5.58 ± 0.29
5.74
4.05 ± 2.95
3.34
2.33 ± 2.79
1.61
3.57 ± 4.28
0.00
Up
LFL
5.22 ± 0.12
5.25
5.33 ± 0.12
5.30
5.18 ± 0.17
5.14
2.77 ± 3.07
0.00
1.34 ± 1.88
0.00
3.88 ± 2.50
3.72
RFL
5.39 ± 0.16
5.46
4.08 ± 0.32
4.10
5.11 ± 0.25
5.25
0.65 ± 1.16
0.00
24.61 ± 12.20
30.52
4.75 ± 3.65
3.51
RHL
5.79 ± 0.11
5.79
5.00 ± 0.35
5.02
5.50 ± 0.14
5.47
1.29 ± 1.72
0.00
9.26 ± 6.38
9.13
2.55 ± 2.04
3.57
LHL
5.76 ± 0.16
5.77
5.78 ± 0.08
5.79
5.70 ± 0.08
5.69
1.97 ± 2.62
0.00
0.10 ± 0.18
0.00
0.72 ± 1.14
0.00
Down
LFL
5.32 ± 0.23
5.40
5.34 ± 0.19
5.42
5.25 ± 0.17
5.25
3.61 ± 3.67
1.67
2.41 ± 2.41
1.56
3.02 ± 3.02
1.72
RFL
5.11 ± 0.14
5.07
3.62 ± 0.40
3.68
4.88 ± 0.26
4.92
4.86 ± 3.40
5.03
40.84 ± 10.27
40.78
10.60 ± 6.47
12.02
RHL
5.53 ± 0.22
5.47
4.49 ± 0.37
4.46
5.21 ± 0.14
5.27
3.77 ± 3.03
3.77
19.57 ± 7.85
20.00
5.16 ± 1.70
4.17
LHL
5.65 ± 0.21
5.72
5.69 ± 0.13
5.69
5.65 ± 0.08
5.64
2.70 ± 2.70
1.79
0.76 ± 1.21
0.00
0.83 ± 1.34
0.00
RFL: right forelimb, LFL: left forelimb, RHL: right hind limb, LHL: left hind limb, B: baseline, PI 7: post-ischemic day 7, PI 28: post-ischemic day 28. Median values are given to show variability of data.
