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Stroke Research and Treatment
Volume 2013, Article ID 840265, 5 pages
Review Article

Detection of Paroxysmal Atrial Fibrillation in Stroke/Tia Patients

1Department of Neurology, University of Massachusetts, USA
2Department of Neurology, Henry Ford Hospital, USA

Received 25 January 2013; Accepted 4 March 2013

Academic Editor: V. Padma

Copyright © 2013 Muhib Khan and Daniel J. Miller. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


One-third of stroke and transient ischemic attack (TIA) are cryptogenic, and paroxysmal atrial fibrillation (PAF) has been suggested as a possible cause for these cryptogenic strokes. Multiple studies have recently evaluated long-term cardiac rhythm monitoring with good yield for PAF. The duration of monitoring varies between studies as well as the qualifying event definition. Moreover, the clinical significance of very brief atrial fibrillation events is unclear in the literature. This paper provides an overview of current advances in the detection of paroxysmal atrial fibrillation, the clinical and genetic factors predictive of arrhythmia detection, and the therapeutic dilemma concerning this approach.