Research Article

Influence of Medication on Fatigue Six Months after Stroke

Table 1

Demographic and clinical characteristics overall and according to 6-month poststroke fatigue.

Overall ()Poststroke fatigue value
No ()Yes ()

Demographic variables
Age, mean ± standard deviation63.6 ± 12.862.3 ± 12.564.7 ± 13.10.24
Men93 (60.8)49 (68.1)44 (54.3)0.082

Vascular risk factors
Hypertension84 (54.9)38 (52.8)46 (56.8)0.62
Diabetes mellitus20 (13.1)7 (9.7)13 (16.0)0.25
Dyslipidemia72 (47.1)30 (41.7)42 (51.9)0.21
Smoking33 (21.6)13 (18.1)20 (24.7)0.32
Alcohol consumption15 (9.8)5 (6.9)10 (12.3)0.26

Medical history
Coronary heart disease35 (22.9)12 (16.7)23 (28.4)0.085
Previous stroke or transient ischemic attack25 (16.3)12 (16.7)13 (16.0)0.92
Cancer14 (9.2)9 (12.5)5 (6.2)0.18
Depression13 (8.5)8 (11.1)5 (6.2)0.27

Stroke characteristics
6-month NIHSS, median0 (0–11)0 (0–6)0 (0–11)0.060
Score ≥ 156 (36.6)21 (29.2)35 (43.3)0.072
6-month Barthel Index score = 100 (complete recovery)137 (89.5)68 (94.4)69 (85.2)0.062
Infarct location
Right62 (40.5)34 (47.2)28 (34.6)0.24
Left64 (41.8)24 (33.3)40 (49.4)
Posterior fossa21 (13.7)11 (12.3)10 (12.3)
Multiple6 (3.9)3 (4.2)3 (3.7)

Emotional and sleep disturbances
Depression32 (20.9)10 (13.9)22 (27.2)0.025
Anxiety64 (41.8)22 (30.6)42 (51.9)0.003
Sleep disturbances79 (51.6)30 (41.7)49 (60.5)0.005
Sleep apnea syndrome12 (7.8)5 (6.9)7 (8.6)0.70

Values are expressed as number (%) unless otherwise indicated.