Influence of Medication on Fatigue Six Months after Stroke

Table 4

Association of the Chalder Fatigue Scale (CFS) score and medication use 6 months after stroke onset.

	⁢Median (IQR) of CFS by use or nonuse of medications		value	value
	No use	Use
6-month treatment
Statin	3 (1–6)	4 (1–6)	0.70	0.23
Beta-blocker	3 (1–6)	4 (2–7)	0.15	0.14
Anxiolytic	4 (1–6)	6 (2.5–9.5)	0.017	0.61
Hypnotic	4 (1–6)	4 (2–6)	0.76	0.66
Antidepressant	3 (1–6)	7 (5–9)	<0.001	0.059
Antihypertensive	1 (0–5)	4 (2–6)	0.033	0.072
Antidiabetes medications	4 (1–6)	4 (2–7)	0.28	0.36
Antiplatelet drug	4 (1–6)	4 (1–6)	0.97	0.23
Anticoagulant	4 (1–6)	4 (1–6)	0.98	0.24
Number of treatments			<0.001	0.039

Unadjusted values (Mann-Whitney test or Spearman Rank Correlation () for number of treatments).
Adjusted values on gender, coronary heart disease history, 6-month Barthel Index (<100), depression score, anxiety score, and sleep disturbances (linear regression model on rank-transformed data after handling missing values on covariates by multiple imputation).