Increased Blood Pressure Variability Is Associated with Worse Neurologic Outcome in Acute Anterior Circulation Ischemic Stroke
Table 3
Ordinal logistic regression models with predictor variables of systolic BPV and mean SBP fitted to the outcomes; (a) columns 2–4: one-point shift in mRS, (b) columns 5–7: bad outcome (mRS 3–6), and (c) columns 8–10: death.
Variable
OR for 1-point mRS shift
95% CI
value
Adjusted OR for 1-point mRS
95% CI
value
OR for death at follow-up
95% CI
value
0–24 hours ()
SBP CV
2.32
1.35–4.00
0.002
2.06
1.09–3.92
0.03
2.97
1.54–5.74
0.001
SBP SD
1.99
1.34–2.96
0.001
1.61
1.02–2.55
0.04
2.29
1.42–3.69
0.001
SBP SV
1.83
1.32–2.54
<0.001
1.83
1.22–2.74
0.01
1.94
1.33–2.85
0.001
Mean SBP
1.02
1.00–1.03
0.02
1.00
0.99–1.02
1.00
1.01
0.99–1.03
0.09
0–72 hours ()
SBP CV
3.38
1.73–6.59
<0.001
2.32
1.03–5.21
0.04
5.62
2.40–13.1
<0.001
SBP SD
2.56
1.55–4.23
<0.001
1.70
0.95–3.04
0.08
3.32
1.80–6.13
<0.001
SBP SV
2.45
1.48–4.07
0.001
2.18
1.20–3.96
0.01
2.72
1.49–4.95
0.001
Mean SBP
1.01
1.00–1.03
0.08
1.00
0.99–1.02
0.72
1.01
0.99–1.03
0.29
0–120 hours ()
SBP CV
4.33
1.94–9.69
<0.001
3.16
1.25–7.94
0.02
8.79
2.92–26.5
<0.001
SBP SD
3.07
1.72–5.49
<0.001
1.98
1.05–3.74
0.04
4.13
1.95–8.74
<0.001
SBP SV
2.88
1.57–5.29
0.001
2.32
1.20–4.49
0.01
2.81
1.35–5.87
0.01
Mean SBP
1.01
0.99–1.02
0.20
1.00
0.98–1.02
0.96
1.00
0.98–1.03
0.65
Adjusted for admission NIHSS, patient age, history of atrial fibrillation, history of diabetes mellitus, endovascular therapy, IV tPA administration, and premorbid mRS.
