Increased Blood Pressure Variability Is Associated with Worse Neurologic Outcome in Acute Anterior Circulation Ischemic Stroke
Table 4
Ordinal logistic regression models fitted to a one-point shift in mRS, stratified by proximal vessel occlusion at hospital admission and persistent proximal vessel occlusion, with predictor variables of SBP CV and SBP CV in a multivariable model.
Variable
OR for 1-point mRS shift
95% CI
value
OR for 1-point mRS shift
95% CI
value
0–24 hours ()
Cohort
Proximal vessel occlusion at hospital admission ()
No proximal vessel occlusion at hospital admission ()
SBP CV
3.13
1.53–6.42
0.002
1.02
0.39–2.67
0.98
Adjusted SBP CV
3.81
1.68–8.65
0.001
0.64
0.22–1.90
0.42
Cohort
Persistent proximal vessel occlusion ()
No persistent proximal vessel occlusion ()
SBP CV
4.32
1.09–17.1
0.04
2.26
1.16–4.38
0.02
Adjusted SBP CV
2.75
0.67–11.3
0.02
2.11
1.00–4.44
0.05
0–72 hours ()
Cohort
Proximal vessel occlusion at hospital admission ()
No proximal vessel occlusion at hospital admission ()
SBP CV
6.03
2.36–15.4
<0.001
0.94
0.29–3.07
0.92
Adjusted SBP CV
5.77
1.99–16.7
0.001
0.49
0.14–1.76
0.27
Cohort
Persistent proximal vessel occlusion ()
No persistent proximal vessel occlusion ()
SBP CV
7.82
1.52–40.2
0.01
2.81
1.21–6.50
0.02
Adjusted SBP CV
15.5
2.27–106
0.01
1.41
0.56–3.56
0.47
0–120 hours ()
Cohort
Proximal vessel occlusion at hospital admission ()
No proximal vessel occlusion at hospital admission ()
SBP CV
7.25
2.38–22.1
<0.001
0.97
0.23–4.13
0.96
Adjusted SBP CV
7.07
2.14–23.4
0.001
0.80
0.17–3.88
0.79
Cohort
Persistent proximal vessel occlusion ()
No persistent proximal vessel occlusion ()
SBP CV
18.1
2.22–148
0.01
3.07
1.11–8.49
0.03
Adjusted SBP CV
48.9
4.08–587
0.002
1.93
0.67–5.61
0.23
Adjusted for admission NIHSS, patient age, endovascular therapy, IV tPA administration, and premorbid mRS.
