Increased Blood Pressure Variability Is Associated with Worse Neurologic Outcome in Acute Anterior Circulation Ischemic Stroke
Table 5
Unadjusted and adjusted ordinal logistic regression models fitted to outcome of mRS with main predictor variable of SBP CV, with models stratified by terciles of mean SBP.
Variable
Unadjusted OR for 1-point mRS shift
95% CI
value
Adjusted OR for 1-point mRS
95% CI
value
0–24 hours ()
SBP CV, lowest SBP tercile
3.76
1.55–9.15
0.01
4.05
1.43–11.5
0.001
(mean SBP 93–123 mmHg)
SBP CV in middle tercile
1.73
0.55–5.46
0.35
0.58
0.15–2.27
0.44
(mean SBP 124–139 mmHg)
SBP CV in highest tercile
1.26
0.46–3.39
0.66
1.41
0.45–4.41
0.56
(mean SBP 140–191 mmHg)
0–72 hours ()
SBP CV in lowest tercile
8.05
2.50–25.9
<0.001
6.39
1.63–25.1
0.003
(mean SBP 84–123 mmHg)
SBP CV in middle tercile
2.61
0.75–9.07
0.13
0.68
0.13–3.72
0.66
(mean SBP 124–138 mmHg)
SBP CV in highest tercile
0.78
0.21–2.89
0.71
1.25
0.31–4.99
0.75
(mean SBP 139–192 mmHg)
0–120 hours ()
SBP CV in lowest tercile
10.5
2.25–48.6
0.002
8.77
1.67–46.2
0.01
(mean SBP 93–123 mmHg)
SBP CV in middle tercile
1.81
0.49–6.65
0.37
1.06
0.23–4.88
0.94
(mean SBP 124–139 mmHg)
SBP CV in highest tercile
1.56
0.30–8.01
0.59
1.47
0.29–7.49
0.64
(mean SBP 140–191 mmHg)
Adjusted for admission NIHSS, patient age, admission glucose, PPVO, and premorbid mRS.
