Stroke Research and Treatment / 2016 / Article / Tab 1

Research Article

Thrombin Generation in Acute Ischaemic Stroke

Table 1

Demographic characteristics of all participants.

CriteriaSubject ()Control ()

Age, mean (SD)71 ± 11.470 ± 17.6
Male, n (%)44 (23.4)26 (37.0)
Ethnicity
 African-Caribbean, (%)58 (30.9)26 (36.6)
 Caucasians, (%)130 (69.1)45 (63.3)
Risk factors
 Hypertension, (%)111 (59.0)7 (9.9)
 Diabetes mellitus, (%)43 (22.3)3 (4.2)
 Smoking, (%)31 (16.5)2 (2.2)
 Atrial fibrillation, (%)43 (22.9)
 Dyslipidaemia, (%)47 (25.0)
 IHD, (%)43 (22.9)
 Peripheral vascular disease, (%)6 (3.2)
 BMI, mean kg/m2 (SD)27.6 ± 5.728 ± 5.6
Medications
 Antiplatelets, (%)14 (7.5)
 Statins, (%)44 (23.4)
 Antihypertensive, (%)59 (31.4)5 (7)
 rtPA, (%)63 (33.5)(—)
 No rtPA, (%)109 (58.0)(—)
Stroke type (TOAST criteria)
 ICH, (%)16 (9.4)(—)
 Large artery atherosclerosis, (%)35 (20.5)(—)
 Lacunar, (%)67 (39.4)(—)
 Cardioembolic, (%)39 (22.9)(—)
 Unknown, (%)9 (5.2)(—)
 Other causes, (%)4 (2.3)(—)
Time to acquisition of tested variables
 NIHSS, median (IQR), min28 (17, 42)(—)
 Barthel index, median (IQR), min28 (17, 42)(—)
 NCCT, median (IQR), hours3.8 (0.5, 23)(—)
 Sample collection, median (IQR), hours19 (10, 36)(—)
 DtN time (rtPA), median (IQR), hours47 (34, 84)(—)

(—): not relevant; IHD: ischaemic heart disease; rtPA: recombinant tissue plasminogen activator; PICH: primary intracerebral haemorrhage; NIHSS: National Institute of Health Stroke scale; NCCT: noncontrast computerised tomography; DtN: door to needle time.

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