Stroke Research and Treatment / 2016 / Article / Tab 3

Research Article

Thrombin Generation in Acute Ischaemic Stroke

Table 3

Thrombin generation in ischaemic stroke subtypes.

CategoryNoncardioembolic
time 1 ()
time 2 (80)
Cardioembolic
time 1 ()
time 2 ()
value

Thrombin generation assays
Median lag time 1, min (IQR)3.3 (2.9, 4.0)3.6 (3.2, 4.7)0.005
Median lag time 2, min (IQR)3.5 (2.9, 4.2)4.0 (3.1, 4.9)0.004
 Median difference, 95% CI−0.20 (−0.61–0.21)−0.40 (−1.06–0.26)
Mean ETP 1, nm min (SD)0.50
Mean ETP 2, nm min (SD)0.81
 Mean difference, 95% CI51.00 (−55.10–157.0)120 (−18.08–258.08)
Median ttP 1, min (IQR)3.3 (2.9, 4.0)3.6 (3.2, 4.7)0.002
Median ttP 2, min (IQR)5.9 (5.3, 6.6)6.8 (5.8, 7.7)0.05
 Median difference, 95% CI−0.20 (−0.60–0.21)−0.20 (−0.86–0.46)
Mean peak 1, nm (SD)0.94
Mean peak 2, nm (SD)0.87
 Mean difference, 95% CI−13.0 (−34.19–8.19)1.00 (−29.74–31.74)
Standard haemostatic markers
Median D-dimer 1, ng/mL (IQR)1215 (590, 2670)1480 (770, 3780)0.0001
Median D-dimer 2, ng/mL (IQR)1120 (480, 2960)1275 (720, 2210)0.0001
 Median difference, 95% CI95 (−61.82–251.82)205 (−136.17–546.17)
Mean fibrinogen 1, g/L (SD)0.66
Mean fibrinogen 2, g/L (SD)0.90
 Mean difference, 95% CI−0.60 (−0.99–−0.21)−0.90 (−1.49–−0.31)

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