Research Article
Safety and Efficacy of Acute Clopidogrel Load in Patients with Moderate and Severe Ischemic Strokes
Table 1
Demographic and outcome variables according to NIHSS score and load status.
| | | NIHSS 3 or less and loaded | NIHSS 4 or more and loaded | value | | | (42.6%) | (57.4%) |
| | Age, median years (min–max) | 61 (21–90) | 65 (31–99) | <0.001 | | African American, number (%) | 102/155 (65.8%) | 151/209 (72.3%) | 0.341 | | Gender, number of females (%) | 67/155 (43.2%) | 98/209 (46.9%) | 0.487 | | Hyperlipidemia | 66/155 (42.6%) | 95/208 (45.7%) | 0.557 | | HTN | 119/155 (76.8%) | 174/208 (83.6%) | 0.100 | | Smoking | 63/154 (40.9%) | 78/205 (38.1%) | 0.583 | | DM | 55/153 (35.95%) | 74/204 (36.27%) | 0.949 | | Prior stroke | 50/155 (32.26%) | 107/209 (51.20%) | <0.001 | | Daily alcohol | 12/81 (14.81%) | 16/106 (15.09%) | 0.958 | | Glucose on admission | 108 (68–495) | 116 (57–574) | 0.199 | | Atrial fibrillation | 6 (3.9%) | 21 (10.5%) | 0.022 | | Dual Plavix and aspirin | 141 (92.2%) | 184 (91.5%) | 0.835 | | Length of stay, median (min–max) | 3 (1–39) | 7 (1–52) | <0.001 | | Inpatient complications | 11/87 (12.7%) | 54/137 (39.4%) | <0.001 | | UTI | 5/155 (3.2%) | 31/209 (14.8%) | <0.001 | | Pneumonia | 2/155 (1.3%) | 17/208 (8.2%) | 0.004 | | Recurrent thrombotic events | 29/153 (19.0%) | 86/206 (41.8%) | <0.001 | | Neuroworsening% | 26/153 (17.0%) | 81/208 (38.9%) | <0.001 | | TOAST | | | 0.342 | | Cardioembolic | 27/155 (17.4%) | 49/209 (23.4%) | | | Large vessel | 36/155 (23.2%) | 57/209 (27.3%) | | | Small vessel | 50/155 (932.3%) | 56/209 (26.8%) | | | Cryptogenic > 1 cause | 5/155 (3.2%) | 3/209 (1.4%) | | | Cryptogenic no cause | 25/155 (16.1%) | 25/209 (12.0%) | | | Other (no vessel dissection) | 12/155 (7.7%) | 19/209 (9.1%) | | | Hemorrhagic infarct in 36 h on F/uCT1 or F/uCT2 | 3/52 (5.8%) | 24/99 (24.2%) | 0.006 | | Symptomatic hemorrhage F/uCT1 or F/uCT2 | 1/60 (1.7%) | 2/114 (1.8%) | 1.000 |
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