Stroke Research and Treatment / 2016 / Article / Tab 1

Research Article

Safety and Efficacy of Acute Clopidogrel Load in Patients with Moderate and Severe Ischemic Strokes

Table 1

Demographic and outcome variables according to NIHSS score and load status.

NIHSS 3 or less and loadedNIHSS 4 or more and loaded value
(42.6%) (57.4%)

Age, median years (min–max)61 (21–90)65 (31–99)<0.001
African American, number (%)102/155 (65.8%)151/209 (72.3%)0.341
Gender, number of females (%)67/155 (43.2%)98/209 (46.9%)0.487
Hyperlipidemia66/155 (42.6%)95/208 (45.7%)0.557
HTN119/155 (76.8%)174/208 (83.6%)0.100
Smoking63/154 (40.9%)78/205 (38.1%)0.583
DM55/153 (35.95%)74/204 (36.27%)0.949
Prior stroke50/155 (32.26%)107/209 (51.20%)<0.001
Daily alcohol12/81 (14.81%)16/106 (15.09%)0.958
Glucose on admission108 (68–495)116 (57–574)0.199
Atrial fibrillation6 (3.9%)21 (10.5%)0.022
Dual Plavix and aspirin141 (92.2%)184 (91.5%)0.835
Length of stay, median (min–max)3 (1–39)7 (1–52)<0.001
Inpatient complications11/87 (12.7%)54/137 (39.4%)<0.001
UTI5/155 (3.2%)31/209 (14.8%)<0.001
Pneumonia2/155 (1.3%)17/208 (8.2%)0.004
Recurrent thrombotic events29/153 (19.0%)86/206 (41.8%)<0.001
Neuroworsening%26/153 (17.0%)81/208 (38.9%)<0.001
TOAST0.342
 Cardioembolic27/155 (17.4%)49/209 (23.4%)
 Large vessel36/155 (23.2%)57/209 (27.3%)
 Small vessel50/155 (932.3%)56/209 (26.8%)
 Cryptogenic > 1 cause5/155 (3.2%)3/209 (1.4%)
 Cryptogenic no cause25/155 (16.1%)25/209 (12.0%)
 Other (no vessel dissection)12/155 (7.7%)19/209 (9.1%)
Hemorrhagic infarct in 36 h on F/uCT1 or F/uCT23/52 (5.8%)24/99 (24.2%)0.006
Symptomatic hemorrhage F/uCT1 or F/uCT21/60 (1.7%)2/114 (1.8%)1.000

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