Longitudinal Study on Low-Dose Aspirin versus Placebo Administration in Silent Brain Infarcts: The Silence Study

Table 5

Secondary endpoint-b: change (last follow-up versus baseline) in cognitive indexes.

	ASA	controls	p-value
Change in the Psychomotor speed score
LOCF Δ (last-first) Mean (SD)	-0.03 (0.17)	-0.04 (0.54)	0.3205
NON IMPUTED Δ (last-first) Mean (SD)	0.07 (0.05)	0.19 (0.99)	0.3082
Change in the Memory performance score
LOCF Δ (last-first) Mean (SD)	-0.29 (0.61)	-0.08 (0.74)	0.2238
NON IMPUTED Δ (last-first) Mean (SD)	0.14 (0.41)	-0.08 (0.91)	0.3747
Change in the Global cognitive index score
LOCF Δ (last-first) Mean (SD)	-0.20 (0.46)	-0.12 (0.51)	0.2507
NON IMPUTED Δ (last-first) Mean (SD)	-0.07 (0.34)	-0.03 (0.61)	0.8353