Stroke Research and Treatment / 2018 / Article / Tab 5

Clinical Study

Longitudinal Study on Low-Dose Aspirin versus Placebo Administration in Silent Brain Infarcts: The Silence Study

Table 5

Secondary endpoint-b: change (last follow-up versus baseline) in cognitive indexes.

ASAcontrolsp-value

Change in the Psychomotor speed score
 LOCF Δ (last-first) Mean (SD)-0.03 (0.17)-0.04 (0.54)0.3205
 NON IMPUTED Δ (last-first) Mean (SD) 0.07 (0.05)0.19 (0.99)0.3082

Change in the Memory performance score
 LOCF Δ (last-first) Mean (SD)-0.29 (0.61)-0.08 (0.74)0.2238
 NON IMPUTED Δ (last-first) Mean (SD) 0.14 (0.41)-0.08 (0.91)0.3747

Change in the Global cognitive index score
 LOCF Δ (last-first) Mean (SD)-0.20 (0.46)-0.12 (0.51)0.2507
 NON IMPUTED Δ (last-first) Mean (SD) -0.07 (0.34)-0.03 (0.61)0.8353

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